Other promising areas of research that may illumine the exact molecular nature of exercise-induced protein remodeling in muscle may be the study of related proteins involved with cell architecture, such as desmin and dystrophin . These proteins are thought to provide the cellular scaffolding necessary for the actin-myosin complex to undergo contraction. Research on desmin revealed that its presence increased greatly in a test group exposed to resistance training, while there was no evidence of desmin increase with endurance training. According to this study, there was no detectable increase in dystrophin in resistance or endurance training.  It may be that exercise-induced myofilament alterations involve more than the contractile proteins actin & myosin.
Great, great article. I’ve got a few questions, however. I’ve been lifting now for about 5 years, and really only a month or so have been SMART training (diet in check by tracking, progressive overloading in the 4-6 rep range, essentially following BLS) and have made substantial progress on cutting. Does this mean I’m technically a beginner by these terms, being that I’ve trained for years but only recently started becoming fully educated? Should I be cutting first? My plan was (starting at ~15% BF) to get down to about 8 or 9 (I am roughly 11-12% now). Should I be cutting that low, or bulk earlier to cash in on “genetic potential”?