Effects of androgenic-anabolic steroids in athletes

The meta-analysis (1) mainly included trials, sponsored by product makers, of short duration that were designed to assess surrogate endpoints.  A somewhat similar meta-analyses about DPP-4 inhibitors in diabetic patients showed significant and impressive mortality reductions, whereas a subsequent larger meta-analysis (5), with more trials designed to assess hard endpoints, showed no effect on mortality, and an increased risk of heart failure: RR (95% CI to ).
In conclusion, more research is needed, recruiting patients with higher baseline death risk in trials with well-balanced arms and adequate duration, before promoting this new costly drug class, of uncertain long-term safety.

Effects of androgenic-anabolic steroids in athletes

effects of androgenic-anabolic steroids in athletes

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