This form if injection is used in treating many skin conditions including acne lesions, cysts, alopecia (bald spots), eczema , abundant scar tissue (keloids, hypertrophic scars), psoriasis , lichen simplex chronicus, skin lupus, granuloma annulare, and more. Intralesional injections are extremely helpful, as they are able to bypass the outer defensive layers of the skin to reach an area that will make the greatest impact on your condition. It is common for a patient to need multiple injections, as different cases vary in severity.
Indications for intralesional corticosteroid therapy are acute and chronic inflammatory processes [ 4 ], hyperplastic and hypertrophic skin disorders, and conditions that typically have a favorable response to systemic and topical corticosteroids. In addition to anti-inflammatory properties, the atrophogenic side effect of corticosteroids also can be used advantageously when treating hypertrophic types of lesions, including hypertrophic scars and keloids, lichen simplex chronicus, hypertrophic discoid lupus erythematosus, psoriasis, and cutaneous sarcoidosis (ie, lupus pernio).
Intralesional injection of a steroid is done as an out-patient procedure, with no special preparation involved. You should tell the doctor if you have any allergies or problems with your general health. Although the area to be treated can be numbed with a local anesthetic, this is not normally necessary: the discomfort associated with the steroid injection is very similar to that caused by an injection of local anesthetic. Depending on the size of the area to be treated, a number of injections may be required.
Your doctor will probably place a small dressing over the injected site, and this can be removed after a few hours. Depending on the condition being treated, you may be offered further treatment sessions, at least several weeks apart.