Several brands of IVIG have been approved by the Food and Drug Adminsitration (FDA) (see table in Appendix). There is a lack of reliable evidence that any one brand of IVIG is more effective than other brands. However, immune globulin products may differ from each other in ways that may be important in a particular patient. Different manufacturers then use various combinations of precipitation and/or chromatography steps to obtain a final preparation that consists of greater than 95 % IgG in all currently available products. The various manufacturers also use different final purification steps and stabilizers to obtain their final products, which may then vary in storage requirement and shelf life. In several currently available products, stabilizers include sugars, such as sucrose, glucose, or maltose. Other products contain amino acids such as glycine and proline. The sodium content of different products also varies.
What was my root cause? The evidence led us to conclude that heavy metal poisoning and resulting severe inflammation triggered my Hashimoto’s. During the summer of 2008, I had a large amalgam filling removed from one of my molars. The dentist didn’t take the proper precautions during the very long procedure. For three hours I breathed the vapors as he drilled the amalgam from my mouth. Amalgam is approximately 50% mercury . As soon as I sat up, I felt sick. I stumbled out of the office and spent the next week mostly in bed, exhausted and without energy. My health quickly deteriorated from that point on.