Transdermal patches can be a very precise time released method of delivering a drug. Cutting a patch in half might affect the dose delivered. The release of the active component from a transdermal delivery system (patch) may be controlled by diffusion through the adhesive which covers the whole patch, by diffusion through a membrane which may only have adhesive on the patch rim or drug release may be controlled by release from a polymer matrix. Cutting a patch might cause rapid dehydration of the base of the medicine and affect the rate of diffusion.
Pathologic phimosis is a common problem throughout the world. In Europe, Asia, South America, and Central America neonatal circumcision is not routinely performed, thus childhood phimosis is not rare. In addition, in the United States and Canada the rates of neonatal circumcision, estimated to be 60% to 90%, 5 are declining. 9 Thus, even in the United States and Canada, phimosis is a commonly faced problem. Obviously, one of the difficulties that arises when studying phimosis is the lack of a clear definition and differentiation between a pathologic phimosis and a physiologic nonretractile foreskin. 10 In our study, nonretractable and pinpoint prepuces correspond to type II and type I of the classification by Kayaba et al. 11 The cases classified as ''retractable'' phimosis might not be considered pathologic by others because of a potential for spontaneous resolution with increasing age. However, all patients included in our study were originally referred for circumcision, they all had a constrictive ring for which they had sought medical attention, and they would have been considered candidates for circumcision if topical therapy had not been offered. [CIRP note: These doctors show the common inability to distinguish between normal in childhood developmentally narrow foreskin and a pathological condition called phimosis.]
Mometasone is classed as a potent topical corticosteroid. Topical corticosteroids are also referred to as topical steroids . Topical steroids are used in addition to moisturisers (emollients) for treating inflammatory skin conditions such as eczema and dermatitis . A topical steroid is used when patches of eczema or dermatitis flare up. Mometasone relieves the symptoms of a flare-up by reducing inflammation, itching and redness. It is not a cure for the condition, but it will help to relieve the symptoms. Short courses of mometasone may also be prescribed for the treatment of psoriasis for small areas such as the scalp, soles of the feet, or palms of the hands.